Ozempic (semaglutide) is an injectable prescription medication originally approved by the FDA in 2017 for treating type 2 diabetes. More recently, it has gained popularity as an “off-label” treatment for chronic weight management.

Ozempic helps people lose weight by curbing appetite and reducing food cravings. It also slows digestion to promote feelings of fullness and satisfaction after eating.

For many people struggling with obesity or being overweight, Ozempic can be an effective addition to diet, exercise, and behavior changes for long-term weight loss.

The question, however, is: how long can you stay on Ozempic for weight loss?

blue tape measuring on clear glass square weighing scale

Clinical Trials

Clinical trials have shown that Ozempic can lead to significant weight loss in people with obesity and overweight.

In one study, researchers sought to evaluate the efficacy of Ozempic for weight loss among participants with a body mass index (BMI) of 30 or more.

The core focus was to observe any marked changes in body weight, BMI, and related metabolic factors over a 68-week period.

The clinical outcomes were undoubtedly promising. Participants who received a weekly dose of Ozempic reported an average weight loss of 14.9% of their body weight, compared to the placebo group, who lost only 2.4%.

The degree of weight loss surpassed that typically seen with most approved weight loss drugs, suggesting Ozempic’s potential role as a game-changer in weight reduction.

While Ozempic showed an impressive weight-loss potential, it also presented some side effects. Participants reported:

  • nausea
  • diarrhea
  • constipation
  • vomiting

although these side effects were generally mild and lessened over time.

The Bottom Line

So generally speaking, how long you can stay on Ozempic is something you should discuss with your doctor.
What is clear is that taking Ozempic for weight loss can be much more effective when combined with certain lifestyle changes.

The drug alone may lead to some weight loss, but making dietary and exercise modifications can further accelerate your results.